Posts Tagged ‘Treatment of Psoriasis’
Patient-reported outcomes of adalimumab, phototherapy, and placebo in the Vascular Inflammation in Psoriasis Trial: A randomized controlled study
Philadelphia, Pennsylvania; Los Angeles, California; Salt Lake City, Utah; Williamsville, New York; Dallas, Texas; Portland, Oregon; Norfolk, Virginia; and Bethesda, Maryland J AM ACAD DERMATOL OCTOBER 2019 Background: There are limited data about the impact of narrowband ultraviolet B phototherapy on patient-reported measures of health-related quality of life. Objective: To evaluate the impact of adalimumab…
Read MoreUnderstanding NB-UVB Phototherapy
Narrowband UVB has become the phototherapy treatment of choice for psoriasis, vitiligo, atopic dermatitis (eczema), and other photoresponsive skin disorders. Understanding the benefits of “Narrowband” UVB versus conventional “Broadband” UVB phototherapy requires an understanding of light and the processes it affects. The spectrum of optical radiation (light) is made up of different wavelengths of “light”…
Read MoreWhy NB-UVB?
In most cases, it is preferable to use narrow band UVB (NB-UVB) light, since there is no need for systemic drugs like Methoxsalen and treatment times are short. Recent studies show that the use NB-UVB results in faster responses and longer remissions than with UVB broadband. Using narrowband UVB, results are similar to a PUVA…
Read MoreA Perspective on the Use of NB-UVB Phototherapy vs. PUVA Photochemotherapy
Sally H. Ibbotson* Photobiology Unit, Dermatology Department, Ninewells Hospital, University of Dundee School of Medicine, Dundee, United Kingdom Narrowband UVB (NB-UVB) phototherapy and psoralen-UVA (PUVA) photochemotherapy are widely used phototherapeutic modalities for a range of skin diseases. The main indication for NB-UVB and PUVA therapies is psoriasis, and other key diagnoses include atopic eczema, vitiligo,…
Read MorePsoriasis: General principles for phototherapy
All patients who are considered for treatment with phototherapy or photochemotherapy must have a complete history and physical examination. Patients with a known history of lupus erythematosus or xeroderma pigmentosum should not be treated with phototherapy or photochemotherapy. Patients with a history of a photosensitivity disorder, taking photosensitizing medications, with a history of melanoma, with…
Read MoreNarrowband UVB Phototherapy for the Treatment of Psoriasis
With approximately 150,000 newly diagnosed cases of psoriasis each year, this chronic skin disease affects approximately 2% of the US population and causes considerable morbidity.(1) First-stage treatment of patients with moderate- to-severe psoriasis often starts with topical agents and then progresses to phototherapy (UVB) for more extensive disease. Extensive disease that cannot be controlled adequately…
Read More